By Vasant V. Ranade, Mannfred A. Hollinger, John B. Cannon
Drug supply applied sciences characterize an unlimited and very important quarter of analysis and improvement. The call for for cutting edge drug supply platforms maintains to develop, and this development maintains to force new advancements. development at the starting place supplied by means of the 1st version, Drug supply structures, moment variation covers the newest advancements in either and academia. New during this variation: bankruptcy concentrating on novel applied sciences and their international outlookCoverage of electronically managed drug deliveryMacrocapsules and nanoparticles in drug targetingDrug nanocrystals and different new supply systemsUpdated details on liposomes as providers Written in an easy, transparent, and concise demeanour, the writer presents an international point of view on present and destiny advances and industry possibilities. Drug supply platforms, moment version solutions the necessity for complete info in one source for someone venturing into this region of drug improvement.
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Extra info for Drug Delivery Systems, Second Edition (Pharmacology and Toxicology: Basic and Clinical Aspects)
J. , 24, 485–491, 1972. 50. , New aspects of liposomes, Biochim. Biophys. Acta, 457, 259, 1976. 51. , Targeting of drugs, NATO-ASI Series A, 47, Plenum Press, New York and London, 1983. 52. , Liposomes in therapeutic and preventive medicine. The development of drug carrier concept, Ann. Y. Acad. , 308, 343, 1978. 53. , Selective delivery of drugs encapsulated in liposomes: natural targeting to macrophages involved in various disease states, J. Biol. Response Modiﬁers, 2 ,97–100, 1983. © 2004 by CRC Press LLC 54.
A statistically signiﬁcant, dose-dependent enhancement of protection by liposome-encapsulated MPG was observed. 148 • The nuclear enzyme, topoisomerase I, was recently recognized as the target for the anticancer drug, camptothecin (CPT), and its derivatives. This drug was reported to display effective antitumor effects on a variety of human tumor models xenografted in nude mice. 149 • The authors developed a lipid-based drug delivery system to provide prolonged levels of gentamicin in local tissues after local administration.
75, 325, 1986. 87. Chen, C. , Use of ﬂuidized bed in proliposome manufacturing, J. Pharm. , 76, 419, 1987. 88. , Targeting of macromolecular carriers and liposomes by antibodies to myosin heavy chain, Am. J. , 261, 60–65, 1991. © 2004 by CRC Press LLC 89. , Liposomes from soya phospholipids as percutaneous drug carriers, Arzneimittelforschung, 40, 1365–1368, 1990. 90. , Activity of amphipathic poly(ethylene glycol) 5000 to prolong the circulation time of liposomes depends on the liposome site, Biochim.
Drug Delivery Systems, Second Edition (Pharmacology and Toxicology: Basic and Clinical Aspects) by Vasant V. Ranade, Mannfred A. Hollinger, John B. Cannon